ChemicalBook > CAS DataBase List > LINDERANE
LINDERANE
- Product Name
- LINDERANE
- CAS No.
- 13476-25-0
- Chemical Name
- LINDERANE
- Synonyms
- linerane;LINDERANE;LINDERANE(RG);wuyaomineizhi;Linderane ,98%;Linderane, 98%, from Lindera aggregata (Sims) Kosterm.;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-2H-10,1a-(epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one;(1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-10,1a-(epoxymethano)-2H-oxireno[4,5]cyclodeca[1,2-b]furan-12-one;2H-10,1a-(Epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one,3,6,10,10a-tetrahydro-5,9-dimethyl-, (1aS,4E,10S,10aS)-
- CBNumber
- CB9243408
- Molecular Formula
- C15H16O4
- Formula Weight
- 260.29
- MOL File
- 13476-25-0.mol
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LINDERANE Property
- Melting point:
- 190～191℃
- Boiling point:
- 434.5±45.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- solubility
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
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Safety
- Safety Statements
- 24/25
- HS Code
- 29322090
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- PHL80489
- Product name
- Linderane
- Purity
- phyproof? Reference Substance
- Packaging
- 10mg
- Price
- $629
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27479
- Product name
- Linderane
- Packaging
- 5mg
- Price
- $44
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27479
- Product name
- Linderane
- Packaging
- 10mg
- Price
- $78
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27479
- Product name
- Linderane
- Packaging
- 25mg
- Price
- $151
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 27479
- Product name
- Linderane
- Packaging
- 50mg
- Price
- $278
- Updated
- 2024/03/01
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LINDERANE Chemical Properties,Usage,Production
Description
Linderane is a sesquiterpene that has been found in L. aggregata. It inhibits the cytochrome P450 (CYP) isoform CYP2C9 (Ki = 1.26 μM) in an irreversible and NADPH-dependent manner. Linderane decreases phosphoenolpyruvate carboxykinase (Pck1) and glucose-6-phosphatase (G6pc) gene expression, cAMP concentration, and CREB phosphorylation, increases phosphodiesterase 3 (PDE3) activity, and inhibits gluconeogenesis in rat primary hepatocytes. In vivo, linderane (50 mg/kg twice per day) decreases serum and hepatic triglyceride levels, as well as random-fed and fasting blood glucose levels in ob/ob mice.
Uses
Linderane is a sequiterpene lactone extract from Lindera strychnifolia compound used as a cytotoxic agent against hepaic stellate cells.
Definition
ChEBI: Linderane is a member of dioxanes.
LINDERANE Preparation Products And Raw materials
Raw materials
Preparation Products
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LINDERANE Suppliers
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View Lastest Price from LINDERANE manufacturers
Shanghai Standard Technology Co., Ltd.
- Product
- Linderane 13476-25-0
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2019-10-22
Shanghai Standard Technology Co., Ltd.
- Product
- Linderane 13476-25-0
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- Analytical Standard
- Supply Ability
- 10 g
- Release date
- 2019-10-22
Career Henan Chemical Co
- Product
- LINDERANE 13476-25-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-05-25
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